We’re very proud to announce that The first article based on our partner RISC-19-ICU database has been released on Eclinmed.
Following the critical developments in ICUs in regions experiencing early inception of the COVID-19 outbreak, the European-based, international RIsk Stratification in COVID-19 patients in the Intensive Care Unit (RISC-19-ICU) registry was created to provide near real-time assessment of patients developing critical illness due to COVID-19. The European RISC-19-ICU cohort demonstrates a moderate mortality of 24% in critically ill patients with COVID-19.
Despite high ARDS severity, mechanical ventilation incidence was low and associated with more rescue therapies. In contrast to risk factors in hospitalized patients reported in other studies, the main mortality predictors in these critically ill patients were markers of oxygenation deficit, renal and microvascular dysfunction, and coagulatory activation. Elevated risk of bloodstream infections underscores the need to exercise caution with off-label therapies.